FBLN3 ELISA 试剂盒
Quick Overview for FBLN3 ELISA 试剂盒 (ABIN5510647)
抗原
See all FBLN3 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Fibulin-3/EFEMP1
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: CHO
Immunogen sequence: Q18-F493 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. .
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Fibulin 3 (FBLN3) ELISA Kit
FBLN3 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Plasma, Serum, Urine
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 人 Colorimetric Sandwich ELISA 1.25 ng/mL - 80 ng/mL Plasma, Serum, Tissue Homogenate
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Plasma, Serum
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 小鼠 Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Urine
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 人 Extracellular Colorimetric Sandwich ELISA 1.56-100 ng/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
Fibulin 3 (FBLN3) ELISA KitFBLN3 适用: 小鼠 Extracellular Colorimetric Sandwich ELISA 31.25-2000 pg/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- FBLN3 (Fibulin 3 (FBLN3))
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别名
- EFEMP1
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背景
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Protein Function: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. .
Background: EGF-containing fibulin-like extracellular matrix protein 1 is a protein that in humans is encoded by the EFEMP1 gene. This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
Synonyms: EGF-containing fibulin-like extracellular matrix protein 1,Extracellular protein S1-5,Fibrillin-like protein,Fibulin-3,FIBL-3,EFEMP1,FBLN3, FBNL,
Full Gene Name: EGF-containing fibulin-like extracellular matrix protein 1
Cellular Localisation: Secreted, extracellular space . Secreted, extracellular space, extracellular matrix . Localizes to the lamina propria underneath the olfactory epithelium.. -
UniProt
- Q12805
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途径
- EGFR Signaling Pathway
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