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PDCD1LG2 ELISA 试剂盒

PDCD1LG2 适用: 人 AA 20-220 Colorimetric Sandwich ELISA
产品编号 ABIN5510640
发货至: 中国
  • 抗原 See all PDCD1LG2 ELISA试剂盒
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    抗原表位
    AA 20-220
    适用
    • 3
    • 1
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human PD-L2/B7-DC
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: L20-T220
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all PDCD1LG2 ELISA试剂盒
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    别名
    PDCD1LG2 (PDCD1LG2 产品)
    别名
    PDL2 ELISA Kit, B7DC ELISA Kit, Btdc ELISA Kit, CD273 ELISA Kit, PD-L2 ELISA Kit, PDCD1L2 ELISA Kit, bA574F11.2 ELISA Kit, B7-DC ELISA Kit, F730015O22Rik ELISA Kit, programmed cell death 1 ligand 2 ELISA Kit, PDCD1LG2 ELISA Kit, Pdcd1lg2 ELISA Kit
    背景

    Protein Function: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). .

    Background: Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. It is mapped to chromosome 9p24.2. PD-L2 is one of two ligands for programmed death-1 (PD-1), a member of the CD28 family of immuno-receptors. Northern blot analysis detect wide expression of PDL2, with highest levels in placenta, heart, pancreas, lung, and liver, and lower levels in spleen, lymph nodes, and thymus. PDL2 negatively regulates T cells and plays an essential role in immune tolerance.

    Synonyms: Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2,

    Full Gene Name: programmed cell death 1 ligand 2

    Cellular Localisation: Isoform 3: Secreted
    UniProt
    Q9BQ51
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