TGFB2 ELISA 试剂盒
Quick Overview for TGFB2 ELISA 试剂盒 (ABIN5510608)
抗原
See all TGFB2 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated Dog Caninea TGF-beta 2
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: A303-S414 -
交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Sequence similarities: Belongs to the TGF-beta family.
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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别名
- TGFB2
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背景
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Protein Function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
Background: Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured Dog Caninea anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
Synonyms: Transforming growth factor beta-2,TGF-beta-2,BSC-1 cell growth inhibitor,Cetermin,Glioblastoma-derived T-cell suppressor factor,G-TSF,Polyergin,Latency-associated peptide,LAP,TGFB2,
Full Gene Name: Transforming growth factor beta-2
Cellular Localisation: Secreted. -
UniProt
- P61812
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原 See all TGFB2 ELISA试剂盒
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