Endothelin 1 ELISA 试剂盒
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- 抗原 See all Endothelin 1 (EDN1) ELISA试剂盒
- Endothelin 1 (EDN1)
- 抗原表位
- AA 53-73
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适用
- 犬
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Caninea Endothelin
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: human peptide
Immunogen sequence: C53-W73 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Sequence similarities: Belongs to the endothelin/sarafotoxin family.
Tissue Specificity: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells. .
- Top Product
- Discover our top product EDN1 ELISA Kit
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all Endothelin 1 (EDN1) ELISA试剂盒
- Endothelin 1 (EDN1)
- 别名
- EDN1 (EDN1 产品)
- 背景
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Protein Function: Endothelins are endothelium-derived vasoconstrictor peptides.
Background: The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in Dog Canineas. Three isoforms of Dog Caninea endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure(hypertension) and heart disease.
Synonyms: Endothelin-1,Preproendothelin-1,PPET1,Endothelin-1,ET-1,Big endothelin-1,EDN1,
Full Gene Name: Endothelin-1
Cellular Localisation: Secreted. - UniProt
- P05305
- 途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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