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LGALS1/Galectin 1 ELISA 试剂盒

LGALS1 适用: 人 AA 2-135 Colorimetric Sandwich ELISA
产品编号 ABIN5510585
发货至: 中国
  • 抗原 See all LGALS1/Galectin 1 (LGALS1) ELISA试剂盒
    LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
    抗原表位
    AA 2-135
    适用
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Galectin-1
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli
    Immunogen sequence: A2-D135
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. .

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • You, Tan, Dai, Chen, Xu, Yang, Zhang, Bai, Bie: "MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma." in: Oncotarget, Vol. 7, Issue 35, pp. 57099-57116, (2018) (PubMed).

    Chong, Tang, Xiong, Jiang, Xu, Huang, Wang, Zhou, Shi, Wu, Wang: "Galectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 175, (2017) (PubMed).

  • 抗原 See all LGALS1/Galectin 1 (LGALS1) ELISA试剂盒
    LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
    别名
    LGALS1 (LGALS1 产品)
    别名
    GAL1 ELISA Kit, GBP ELISA Kit, Galectin-1 ELISA Kit, LGAS1 ELISA Kit, LGALS1 ELISA Kit, MGC64502 ELISA Kit, GB10026 ELISA Kit, AA410090 ELISA Kit, Gal-1 ELISA Kit, Galbp ELISA Kit, L-14.5 ELISA Kit, L14 ELISA Kit, Lect14 ELISA Kit, galectin-1 ELISA Kit, Galaptin ELISA Kit, galectin 1 ELISA Kit, galectin-1 ELISA Kit, lectin, galactoside-binding, soluble, 1 L homeolog ELISA Kit, protein enabled ELISA Kit, lectin, galactose binding, soluble 1 ELISA Kit, LGALS1 ELISA Kit, Lgals1 ELISA Kit, CC1G_05003 ELISA Kit, CC1G_05004 ELISA Kit, lgals1.L ELISA Kit, LOC408848 ELISA Kit
    背景

    Protein Function: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. .

    Background: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Its expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. Additionally, Galectin-1 is thought to play a role in creating immune tolerance in pregnancy.

    Synonyms: Galectin-1,Gal-1,14 kDa laminin-binding protein,HLBP14,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,S-Lac lectin 1,LGALS1,

    Full Gene Name: Galectin-1

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    P09382
    途径
    Carbohydrate Homeostasis
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