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LIF ELISA 试剂盒

LIF 适用: 小鼠 AA 24-203 Colorimetric Sandwich ELISA
产品编号 ABIN5510575
发货至: 中国
  • 抗原 See all LIF ELISA试剂盒
    LIF (Leukemia Inhibitory Factor (LIF))
    抗原表位
    AA 24-203
    适用
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse LIF
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli
    Immunogen sequence: S24-F203
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
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    Discover our top product LIF ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all LIF ELISA试剂盒
    LIF (Leukemia Inhibitory Factor (LIF))
    别名
    Lif (LIF 产品)
    别名
    CDF ELISA Kit, DIA ELISA Kit, HILDA ELISA Kit, MLPLI ELISA Kit, LIF, interleukin 6 family cytokine ELISA Kit, leukemia inhibitory factor ELISA Kit, LIF ELISA Kit, Lif ELISA Kit
    背景

    Protein Function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

    Background: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.

    Synonyms: Leukemia inhibitory factor,LIF,Differentiation-stimulating factor,D factor,Lif,

    Full Gene Name: Leukemia inhibitory factor

    Cellular Localisation: Secreted.
    UniProt
    P09056
    途径
    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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