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LIF ELISA 试剂盒

This 小鼠 LIF ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 LIF.
产品编号 ABIN5510575
发货至: 中国

Quick Overview for LIF ELISA 试剂盒 (ABIN5510575)

抗原

See all LIF ELISA试剂盒
LIF (Leukemia Inhibitory Factor (LIF))

抗原表位

AA 24-203

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse LIF

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: E.coli
    Immunogen sequence: S24-F203

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all LIF ELISA试剂盒

    LIF (Leukemia Inhibitory Factor (LIF))

    别名

    Lif

    背景

    Protein Function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

    Background: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.

    Synonyms: Leukemia inhibitory factor,LIF,Differentiation-stimulating factor,D factor,Lif,

    Full Gene Name: Leukemia inhibitory factor

    Cellular Localisation: Secreted.

    UniProt

    P09056

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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