Nerve Growth Factor ELISA 试剂盒
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- 抗原 See all Nerve Growth Factor (NGF) ELISA试剂盒
- Nerve Growth Factor (NGF)
- 抗原表位
- AA 122-241
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适用
- 猴
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate NGF/NGF beta
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: S122-A241 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Sequence similarities: Belongs to the NGF-beta family.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all Nerve Growth Factor (NGF) ELISA试剂盒
- Nerve Growth Factor (NGF)
- 别名
- NGF (NGF 产品)
- 背景
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Protein Function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). .
Background: Nerve growth factor(NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male monkey primate submaxillary gland(MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight(Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is monkey primate 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.
Synonyms: Beta-nerve growth factor,Beta-NGF,NGF,NGFB,
Full Gene Name: Beta-nerve growth factor
Cellular Localisation: Secreted. - UniProt
- P01138
- 途径
- Regulation of Cell Size
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