Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab) ELISA 试剂盒
Quick Overview for Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab) ELISA 试剂盒 (ABIN5067631)
抗原
适用
检测方法
实验类型
检测范围
应用范围
样品类型
-
-
最低检测浓度
- 37 mU/mL
-
原理
- Enzyme Immunoassay For The Quantitative Determination Of Human IgG Autoantibodies Against Oxidised Low Density Lipoprotein In Serum
-
Analytical Method
- Quantitative
-
特异性
- Antibodies against oxLDL,Anti oxidized LDL autoantibodies
-
组件
- plate, assay buffer, wash buffer, standards, cotnrols, conjugate, substrate, stop solution
-
试剂未包括
- pipettes, tubes, reader
-
-
Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab) ELISA Kit
oxLDL Ab 适用: 人 Colorimetric Sandwich ELISA 47-3000 μU/mL Plasma, Serum
Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab) ELISA KitoxLDL Ab 适用: 小鼠 Colorimetric Sandwich ELISA 6.25-400 ng/mL Plasma, Serum
Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab) ELISA KitoxLDL Ab 适用: 大鼠 Colorimetric Sandwich ELISA 3.125-200 ng/mL Plasma, Serum
-
-
样本量
- 20 μL
-
板类型
- Pre-coated
-
实验流程
- Oxidized low density lipoprotein (oLDL) is believed to play a critical role in the development and progression of atherosclerosis. Accumulation of oLDL in macrophages and smooth muscle cells causes foam cell formation, an initial step in the disease. Autoantibodies against oxidatively modified LDL can be used as a parameter that consistently mirrors the occurrence of oxidation processes taking place in vivo. In fact, elevated levels of autoantibodies against oLDL have been detected in the blood stream of patients with coronary artery disease. Moreover, recent studies indicate a correlation between autoantibodies against oLDL and the progression of carotid atherosclerosis. Increased serum concentrations of oLAB have also been described in various diseases such as pre-eclampsia and systemic lupus erythematosus. Decreased oLAB titers were observed during septicemia and myocardial infarction.
-
实验精密度
- Intra-assay (n=8) ≤ 4%, Inter-assay (n=5) ≤ 8%
-
限制
- 仅限研究用
-
-
-
缓冲液
- ≤ 0.1 % Proclin
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
- Anti-Oxidized Low Density Lipoprotein Antibody (oxLDL Ab)
-
别名
- anti-oxLDL antibody
-
物质类
- Antibody
抗原
-
