电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Thymic Stromal Lymphopoietin ELISA 试剂盒

This 小鼠 Thymic Stromal Lymphopoietin ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 Thymic Stromal Lymphopoietin.
产品编号 ABIN4987142
发货至: 中国

Quick Overview for Thymic Stromal Lymphopoietin ELISA 试剂盒 (ABIN4987142)

抗原

See all Thymic Stromal Lymphopoietin (TSLP) ELISA试剂盒
Thymic Stromal Lymphopoietin (TSLP)

适用

  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

0.02-1.0 ng/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • 最低检测浓度

    0.02 ng/mL

    Analytical Method

    Quantitative

    特异性

    Natural and recombinant Mouse TSLP Ligand

    灵敏度

    7 pg/mL

    试剂未包括

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • 应用备注

    Detection Wavelength: 450 nm

    样本量

    20 μL

    实验时间

    3 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原 See all Thymic Stromal Lymphopoietin (TSLP) ELISA试剂盒

    Thymic Stromal Lymphopoietin (TSLP)

    别名

    TSLP

    背景

    Thymic Stromal Lymphopoietin (TSLP) is a member of the B cell-stimulating factor family. Originally identified from the conditioned medium of a mouse thymic stromal cell line that promoted B-cell development, TSLP is expressed in thymus, spleen, kidney, lung, and bone marrow. Mouse TSLP cDNA encodes a 140 amino acid (aa) residue precursor protein with a 19 aa signal sequence. TSLP activity overlaps with that of IL-7, playing a key role in the development of B cells, as well as stimulating the growth of thymocytes and T cells. TSLP stimulates monocytes to produce T cell-attracting chemokines such as TARC (CCL17) and MDC (CCL22). TSLP also activates dendritic cell-primed CD4 T cells to produce Th2 cytokines, including IL-4, IL-5, IL-13, and TNFα. This hematopoietic cytokine binds to a heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rα) and the TSLP-specific chain (TSLPR). Binding induces activation of STAT3 and STAT5 via phosphorylation. Mouse TSLP shares approximately 43 % amino acid sequence identity with human TSLP.
You are here:
Chat with us!