Thymic Stromal Lymphopoietin ELISA 试剂盒
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Quick Overview for Thymic Stromal Lymphopoietin ELISA 试剂盒 (ABIN4987142)
抗原
See all Thymic Stromal Lymphopoietin (TSLP) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 0.02 ng/mL
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Analytical Method
- Quantitative
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特异性
- Natural and recombinant Mouse TSLP Ligand
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灵敏度
- 7 pg/mL
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试剂未包括
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Thymic Stromal Lymphopoietin (TSLP) ELISA Kit
TSLP 适用: 人 Colorimetric Sandwich ELISA 62.5 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitHigh Sensitivity TSLP 适用: 人 Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 人 AA 29-159 Colorimetric Sandwich ELISA 31.2-2000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 小鼠 AA 20-140 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 人 Colorimetric Sandwich ELISA 16-2000 pg/mL Cell Lysate, Plasma, Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 小鼠 Colorimetric Sandwich ELISA 16-1000 pg/mL Cell Lysate, Plasma, Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 人 Colorimetric Sandwich ELISA 3.9-250 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
Thymic Stromal Lymphopoietin (TSLP) ELISA KitTSLP 适用: 人 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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应用备注
- Detection Wavelength: 450 nm
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样本量
- 20 μL
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实验时间
- 3 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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- Thymic Stromal Lymphopoietin (TSLP)
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别名
- TSLP
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背景
- Thymic Stromal Lymphopoietin (TSLP) is a member of the B cell-stimulating factor family. Originally identified from the conditioned medium of a mouse thymic stromal cell line that promoted B-cell development, TSLP is expressed in thymus, spleen, kidney, lung, and bone marrow. Mouse TSLP cDNA encodes a 140 amino acid (aa) residue precursor protein with a 19 aa signal sequence. TSLP activity overlaps with that of IL-7, playing a key role in the development of B cells, as well as stimulating the growth of thymocytes and T cells. TSLP stimulates monocytes to produce T cell-attracting chemokines such as TARC (CCL17) and MDC (CCL22). TSLP also activates dendritic cell-primed CD4 T cells to produce Th2 cytokines, including IL-4, IL-5, IL-13, and TNFα. This hematopoietic cytokine binds to a heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rα) and the TSLP-specific chain (TSLPR). Binding induces activation of STAT3 and STAT5 via phosphorylation. Mouse TSLP shares approximately 43 % amino acid sequence identity with human TSLP.
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