电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CXCL2 ELISA 试剂盒

CXCL2 适用: 小鼠 Colorimetric Sandwich ELISA 0.02-1.0 ng/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
产品编号 ABIN4987024
发货至: 中国
  • 抗原 See all CXCL2 ELISA试剂盒
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    适用
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    0.02-1.0 ng/mL
    最低检测浓度
    0.02 ng/mL
    应用范围
    ELISA
    样品类型
    Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
    Analytical Method
    Quantitative
    特异性
    Natural and recombinant Mouse MIP-2 Ligand
    灵敏度
    7 pg/mL
    试剂未包括
    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
    Featured
    Discover our best selling CXCL2 ELISA Kit
    Top Product
    Discover our top product CXCL2 ELISA Kit
  • 应用备注
    Detection Wavelength: 450 nm
    样本量
    20 μL
    实验时间
    3 h
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C
  • 抗原 See all CXCL2 ELISA试剂盒
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    别名
    MIP-2 (CXCL2 产品)
    别名
    CINC-2a ELISA Kit, GRO2 ELISA Kit, GROb ELISA Kit, MGSA-b ELISA Kit, MIP-2a ELISA Kit, MIP2 ELISA Kit, MIP2A ELISA Kit, SCYB2 ELISA Kit, GRO3 ELISA Kit, Gro2 ELISA Kit, MIP-2 ELISA Kit, Mgsa-b ELISA Kit, Mip2 ELISA Kit, Scyb ELISA Kit, Scyb2 ELISA Kit, Mip-2 ELISA Kit, GROB ELISA Kit, MIP-2alpha ELISA Kit, C-X-C motif chemokine ligand 2 ELISA Kit, chemokine (C-X-C motif) ligand 2 ELISA Kit, CXCL2 ELISA Kit, Cxcl2 ELISA Kit
    背景
    Mouse macrophage inflammatory protein-2 (MIP-2), also known as CXCL2, was originally identified as a heparin-binding protein secreted by an LPS-stimulated mouse macrophage cell line (1). A cDNA clone encoding the protein was isolated from this cell line and characterized (2). Based on its protein and DNA sequences, mouse MIP-2 was classified as a member of the alpha (CXC) chemokine family of inflammatory and immunoregulatory cytokines (3).Mouse MIP-2 cDNA encodes a 100 amino acid residue precursor protein from which the amino-terminal 27 amino acid residues are cleaved to generate the mature mouse MIP-2. The protein sequence of mouse MIP-2 shows approximately 63 % identity to that of mouse KC, another mouse alpha chemokine. Mouse MIP-2 is also 60 % identical to human GROβ and GROγ(2). Based on these protein sequence similarities, it is likely that mouse KC and MIP-2 are homologs of human GROα, β and γ chemokines. Since chemokines with protein sequence homology to human IL-8 have not been identified in mice, it has been suggested that the mouse KC and MIP-2 are functional homologs of human IL-8 in mice (3, 4). A putative mouse homolog of the human IL-8 receptor beta (IL-8 Rβ) has also been cloned. This receptor shows 71 % identity to human IL-8 Rβ and 68 % identity to human IL-8 Rα. Both mouse KC and MIP-2 bind mouse IL-8 Rβ with high affinity (5).Like human IL-8, mouse MIP-2 exhibits potent neutrophil chemotactic activity and may be a key mediator of neutrophil recruitment in response to tissue injury and infection (3, 4). Increased MIP-2 expression has been found to be associated with neutrophil influx in various inflammatory conditions (6 - 10).
    途径
    Cellular Response to Molecule of Bacterial Origin
You are here:
客服