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IL-21 ELISA 试剂盒

This 人 IL-21 ELISA Kit specifically detects IL-21 in Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate) 和 Plasma (EDTA).
产品编号 ABIN4986946
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-21 ELISA 试剂盒 (ABIN4986946)

抗原

See all IL-21 (IL21) ELISA试剂盒
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

31.25-2000 pg/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • 最低检测浓度

    31.25 pg/mL

    Analytical Method

    Quantitative

    特异性

    Natural and recombinant Human IL-21 Ligand

    灵敏度

    15 pg/mL

    试剂未包括

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • 应用备注

    Detection Wavelength: 450 nm

    样本量

    20 μL

    实验时间

    3 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原 See all IL-21 (IL21) ELISA试剂盒

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    Interleukin-21(IL-21) and its receptor play an important role in the regulation of the immune system. IL-21R, also called NILR (novel interleukin receptor), is a type I cytokine receptor with 4 conserved cysteine residues and an extracellular WSXWS motif. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells, stimulation (in conjuction) with IL-4 of IgG production, and induction of apoptotic effects in native B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction appears to play an important role in B and T cell proliferation after antigen stimulation and NK cell maturation.

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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