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IL-2 ELISA 试剂盒

This Pig IL-2 ELISA Kit is a Colorimetric ELISA Kit designed to quantify Pig IL-2.
产品编号 ABIN4986945
发货至: 中国

Quick Overview for IL-2 ELISA 试剂盒 (ABIN4986945)

抗原

See all IL-2 (IL2) ELISA试剂盒
IL-2 (IL2) (Interleukin 2 (IL2))

适用

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Pig

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

0.02-1.5 ng/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • 最低检测浓度

    0.02 ng/mL

    Analytical Method

    Quantitative

    特异性

    Natural and recombinant Swine IL-2 Ligand

    灵敏度

    12 pg/mL

    试剂未包括

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • 应用备注

    Detection Wavelength: 450 nm

    样本量

    20 μL

    实验时间

    3 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原 See all IL-2 (IL2) ELISA试剂盒

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes (1, 2). Human IL-2 (also known as T-cell growth factor) is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells promoting proliferation and maturation.IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendocytes. IL-2 is involved in treatment of cancers such as melanoma and renal cell cancer. It plays a key role in promoting the clonal expansion of antigen-specific T cells. In addition, IL-2 has also been shown to mediate multiple immune responses on a variety of cell types. At the amino acid sequence level, there is approximately 72 % similarity between mature porcine and human IL-2.The biological effects of IL-2 are mediated by specific cell surface receptor complexes. The functional high-affinity receptor for IL-2 is composed of three distinct polypeptide chains (3, 4). IL-2 stimulates the proliferation of thymocytes, stimulates the proliferation and differentiation of activated B cells, promotes the growth, differentiation and cytocidal activity of monocytes, induces the growth of natural killer cells and stimulates cytokine production by these cells as well as the cytolytic activity of these cells, enhances the production of lymphocyte-activated killer (LAK) cells, and induces the proliferation and differentiation of oligodendrocytes (1, 2).

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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