IL-2 ELISA 试剂盒
Quick Overview for IL-2 ELISA 试剂盒 (ABIN4986945)
抗原
See all IL-2 (IL2) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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                                            最低检测浓度
- 0.02 ng/mL
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                                            Analytical Method
- Quantitative
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                                            特异性
- Natural and recombinant Swine IL-2 Ligand
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                                            灵敏度
- 12 pg/mL
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                                            试剂未包括
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                        - Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
 
 
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                                            应用备注
- Detection Wavelength: 450 nm
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                                            样本量
- 20 μL
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                                            实验时间
- 3 h
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                                            板类型
- Pre-coated
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                                            限制
- 仅限研究用
 
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                                            储存条件
- 4 °C
 
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    - IL-2 (IL2) (Interleukin 2 (IL2))
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                                            别名
- IL-2
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                                            背景
- Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes (1, 2). Human IL-2 (also known as T-cell growth factor) is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells promoting proliferation and maturation.IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendocytes. IL-2 is involved in treatment of cancers such as melanoma and renal cell cancer. It plays a key role in promoting the clonal expansion of antigen-specific T cells. In addition, IL-2 has also been shown to mediate multiple immune responses on a variety of cell types. At the amino acid sequence level, there is approximately 72 % similarity between mature porcine and human IL-2.The biological effects of IL-2 are mediated by specific cell surface receptor complexes. The functional high-affinity receptor for IL-2 is composed of three distinct polypeptide chains (3, 4). IL-2 stimulates the proliferation of thymocytes, stimulates the proliferation and differentiation of activated B cells, promotes the growth, differentiation and cytocidal activity of monocytes, induces the growth of natural killer cells and stimulates cytokine production by these cells as well as the cytolytic activity of these cells, enhances the production of lymphocyte-activated killer (LAK) cells, and induces the proliferation and differentiation of oligodendrocytes (1, 2).
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                                            途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
 抗原 See all IL-2 (IL2) ELISA试剂盒
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