GM-CSF ELISA 试剂盒
Our Local Distributor
北京 101111
Quick Overview for GM-CSF ELISA 试剂盒 (ABIN4986886)
抗原
See all GM-CSF (CSF2) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
-
-
最低检测浓度
- 0.03 ng/mL
-
Analytical Method
- Quantitative
-
特异性
- Natural and recombinant Mouse GM-CSF Ligand
-
灵敏度
- 15 pg/mL
-
试剂未包括
-
- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
-
-
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA Kit
CSF2 适用: 小鼠 Colorimetric Sandwich ELISA 1.37 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 大鼠 Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 兔 Colorimetric Sandwich ELISA 7.813 pg/mL - 500 pg/mL Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: Cow Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 犬 Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 大鼠 AA 1-127 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 人 AA 18-144 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) ELISA KitCSF2 适用: 小鼠 AA 18-141 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
-
-
应用备注
- Detection Wavelength: 450 nm
-
样本量
- 20 μL
-
实验时间
- 3 h
-
板类型
- Pre-coated
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C
-
-
- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
-
别名
- GM-CSF
-
背景
- Granulocyte macrophage colony-stimulating factor (GM-CSF), a 22 kDa glycosylated protein, was initially characterized as a factor that can support the in vitro colony formation of granulocytemacrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils (1, 2). GM-CSF promotes a Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity (3 5). It shows clinical effectiveness in ameliorating chemotherapyinduced neutropenia, and GM-CSF transfected tumor cells are utilized as cancer vaccines (6, 7). Mature mouse GM-CSF shares 49 % -54 % amino acid sequence identity with canine, feline, human, and porcine GM-CSF and 69 % with rat GM-CSF. GM-CSF exerts its biological effects through a heterodimeric receptor complex composed of GM-CSF Rα/CD116 and the signal transducing common β chain (CD131) which is also a component of the highaffinity receptors for IL-3 and IL-5 (8,9). In addition, GM-CSF binds a naturally occurring soluble form of GM-CSF Rα (10). The activity of GM-CSF is species specific between human and mouse. Mouse GM-CSF is only weakly active on rat cells, although rat GM-CSF is fully active on mouse cells (11).
-
途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原 See all GM-CSF (CSF2) ELISA试剂盒
-
