SOD1 ELISA 试剂盒
Quick Overview for SOD1 ELISA 试剂盒 (ABIN4986813)
抗原
See all SOD1 ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 78 pg/mL
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Analytical Method
- Quantitative
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特异性
- Natural and recombinant Human Cu/ZnSOD Ligand
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灵敏度
- 40 pg/mL
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试剂未包括
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Superoxide Dismutase 1, Soluble (SOD1) ELISA Kit
SOD1 适用: 小鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 大鼠 Colorimetric Competition ELISA 0.16 ng/mL - 10 ng/mL Cell Culture Supernatant, Plasma, Serum
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 人 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Plasma, Serum, Tissue Homogenate
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 大鼠 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Superoxide Dismutase (SOD) Colorimetric Activity KitAcA 适用: 人, Various Species Colorimetric Cell Lysate, Cell Samples, Plasma, Serum, Tissue Samples
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 人 Colorimetric Competition ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma, Serum
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 小鼠 Colorimetric Competition ELISA 0.16 ng/mL - 10 ng/mL Cell Culture Supernatant, Plasma, Serum
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: Cow Colorimetric Sandwich ELISA 0.781 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 犬 Colorimetric Sandwich ELISA 1.563 ng/mL - 100 ng/mL Plasma, Serum, Tissue Homogenate
Superoxide Dismutase 1, Soluble (SOD1) ELISA KitSOD1 适用: 山羊 Colorimetric Sandwich ELISA 0.781 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
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应用备注
- Detection Wavelength: 450 nm
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样本量
- 20 μL
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实验时间
- 3 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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别名
- Cu/ZnSOD
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背景
- Superoxide Dismutases (SODs), originally identified as Indophenoloxidase (IPO), are enzymes that catalyze the conversion of naturallyoccuring but harmful superoxide radicals into molecular oxygen and hydrogen peroxide. Superoxide Dismutases 1, SOD1, also known as Cu/Zn SOD, soluble SOD and IPOA, is a soluble, cytoplasmic 16 kDa homodimer. Each SOD1 monomer binds one Cu2+ and one Zn2+ ion. Three isozymes of SOD have been identified and are functionally related but have very modest sequence homology. SOD1 shares 23 % and 27 % sequence identity with SOD2 and SOD3, respectively. Mutations in SOD1 have been implicated as causes of familial amyotrophic lateral sclerosis (ALS). The ALScausing mutations of SOD1 are scattered throughout the protein and provide no clear functional or structural clues to the underlying disease mechanism. The oligomerization hypothesis suggests that mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight aggregates that result in the death of motor neurons. The oxidative damage hypothesis suggests that loss of function mutation in SOD1 protein results in the accumulation of cellular superoxide radical, leading to free radicalmediated damage, the release of cytochrome c, and apoptosis.
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
抗原 See all SOD1 ELISA试剂盒
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