Several autoantigens have been discussed for celiac disease and Dermatitis herpetiformis recently. Dieterich et al. have described two non-collagenous proteins with an apparent molecular weight of 90 and 300 kDa being the main autoantigens detected by EmA (1). Celiac disease, or gluten-sensitivity, is found already in neonates and is characterized by small intestinal damages leading to a so-called "flat" mucosa. Due to this extensive lesions mal-absorption occurs frequently accompanied with a depletion of key nutrients.
应用备注
Optimal working dilution should be determined by the investigator.
样本量
100 μL
实验时间
2 h
板类型
Pre-coated
实验流程
Celiac EmA (Anti-Endomysium Antibody) IgG ELISA assay kit is an enzyme immunoassay for the quantitative determination of IgG autoantibodies to the supposed major autoantigens in Dermatitis herpetiformis and celiac disease in sample serum.