Endothelin Big ELISA 试剂盒
人 Endothelin Big ELISA Kit, Colorimetric is an assay for quantification of 人 Endothelin Big.
产品编号 ABIN2648509
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Endothelin Big ELISA 试剂盒 (ABIN2648509)
抗原
See all Endothelin Big products
Endothelin Big
适用
人
检测方法
Colorimetric
应用范围
ELISA
样品类型
Serum, Plasma, Plasma (EDTA)
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灵敏度
- 0.02 pmol/L
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产品特性
- Big Endothelin-1 (BigET) is a peptide of 38 amino acids and is the precursor of Endothelin-1 (ET), represented by amino acids 1-21 (http://www.uniprot.org/uniprot/P05305). ET is a potent vasoconstrictor and is produced by vascular endothelial cells. Accordingly it has a wide tissue distribution (http://www.ncbi.nlm.nih.gov/UniGene/ESTProfileViewer.cgi?uglist=Hs.511899). The cleavage of BigET by Endothelin Converting Enzyme (ECE) leads to ET and to a C-terminal fragment. Both BigET and ET are strong independent predictors of survival in patients with congestive heart failure, and identify a population with a very high risk mortality. The half-life of ET (1-21) in plasma is less than one minute, whereas clearance of BigET is much slower. BigET can therefore be determined more easily.
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应用备注
- Optimal working dilution should be determined by the investigator.
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样本量
- 50 μL
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实验时间
- 5.5 h
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板类型
- Pre-coated
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实验流程
- Human Big Endothelin-1 ELISA Assay Kit in serum & plasma. Big Endothelin-1 ELISA Assay Kit is manufactured by Biomedica Gruppe (www.bmgrp.com) and is for research use only, not to be used in diagnostic procedures.
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限制
- 仅限研究用
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储存条件
- 4 °C
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- Endothelin Big
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别名
- Big Endothelin
抗原 See all Endothelin Big products
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