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Granulin ELISA 试剂盒

This Colorimetric ELISA kit is designed for the quantitative measurement of 人 Granulin.
产品编号 ABIN2042639
发货至: 中国
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Quick Overview for Granulin ELISA 试剂盒 (ABIN2042639)

抗原

See all Granulin (GRN) ELISA试剂盒
Granulin (GRN)

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

1.6-100 ng/mL

应用范围

ELISA
  • 最低检测浓度

    1.6 ng/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 50 pg/mL

    组件

    96-well plate pre-coated with anti-Progranulin, Human
    Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all Granulin (GRN) ELISA试剂盒

    Granulin (GRN)

    别名

    Progranulin

    物质类

    Viral Protein

    基因ID

    2896

    UniProt

    P28799
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