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MMP13 ELISA 试剂盒

This 人 MMP13 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 MMP13.
产品编号 ABIN2042611
发货至: 中国

Quick Overview for MMP13 ELISA 试剂盒 (ABIN2042611)

抗原

See all MMP13 ELISA试剂盒
MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

8-5000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    8 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 5 pg/mL

    组件

    96-well plate pre-coated with anti-MMP13, Human
    Lyophilized recombinant MMP13, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human MMP13 in cell culture supernates, serum and plasma (heparin).Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene.[1][2]Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. [3] The expression of MMP13 in osteoarthritic cartilage and its activity against type II collagen indicates that the enzyme plays a significant role in cartilage collagen degradation and must, therefore, form part of a complex target for proposed therapeutic interventions based on collagenase inhibition. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all MMP13 ELISA试剂盒

    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

    别名

    MMP13

    基因ID

    4322

    UniProt

    A8K846
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