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MMP7 ELISA 试剂盒

This 人 MMP7 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 MMP7.
产品编号 ABIN2042607
发货至: 中国

Quick Overview for MMP7 ELISA 试剂盒 (ABIN2042607)

抗原

See all MMP7 ELISA试剂盒
MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

6-10000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    6 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 6 pg/mL

    组件

    96-well plate pre-coated with anti-MMP-7, Human
    Lyophilized recombinant MMP-7, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human MMP-7 in cell culture supernates, serum, plasma (heparin), saliva and urine.Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The PUMP1 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The PUMP I protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis.1 Matrilysin, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, matrilysin mRNA is regulated in a specific and distinct manner in normal and malignant tissues.2 Matrilysin has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined.1 Matrilysin is also a mediator of pulmonary fibrosis and a potential therapeutic target.3 The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28kD. The detected MMP-7 includes zymogen and active enzyme.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all MMP7 ELISA试剂盒

    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

    别名

    MMP-7

    基因ID

    4316

    UniProt

    P09237

    途径

    Production of Molecular Mediator of Immune Response
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