IL-33 ELISA 试剂盒
Quick Overview for IL-33 ELISA 试剂盒 (ABIN2042551)
抗原
See all IL-33 (IL33) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 31.2 pg/mL
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交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 10 pg/mL
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组件
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96-well plate pre-coated with anti-IL-33, Mouse
Lyophilized recombinant IL-33, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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板类型
- Pre-coated
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实验流程
- Sandwich ELISA quantitative detection kit for Mouse IL-33 in cell culture supernates, serum and plasma (heparin, EDTA).Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. By genomic sequence analysis, the IL33 gene is mapped to chromosome 9p24.1 and its mouse homolog to a syntenic region on chromosome 19qC1. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 + T cell (CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- IL-33
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基因ID
- 77125
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UniProt
- Q8BVZ5
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途径
- Production of Molecular Mediator of Immune Response
抗原 See all IL-33 (IL33) ELISA试剂盒
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