IL-33 ELISA 试剂盒
Quick Overview for IL-33 ELISA 试剂盒 (ABIN2042550)
抗原
See all IL-33 (IL33) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 15.6 pg/mL
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品牌
- BioAssay™
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交叉反应 (详细)
- No detectable crossreactivity with other relevant proteins
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灵敏度
- < 10 pg/mL
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组件
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A: Microtiter Strip, 1x96 wells
B: IL-33 Standard, 2x10 ng
C: Anti-human IL-33 (Biotin), 130 µL
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- IL-33
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背景
- Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. The IL33 gene maps to chromosome 9p24.1 by using of genomic database analysis. Recombinant mature human IL33 bound to ST2. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 + T cell (CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.
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途径
- Production of Molecular Mediator of Immune Response
抗原 See all IL-33 (IL33) ELISA试剂盒
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