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CX3CL1 ELISA 试剂盒

This 人 CX3CL1 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 CX3CL1.
产品编号 ABIN2042470
发货至: 中国

Quick Overview for CX3CL1 ELISA 试剂盒 (ABIN2042470)

抗原

See all CX3CL1 ELISA试剂盒
CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

6-10000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    6 pg/mL

    交叉反应 (详细)

    There is detectable cross-reactivity with Eotaxin, MCP-1, MCP-2, 6Ckine, MARC < 0.2 % .

    灵敏度

    < 50 pg/mL

    组件

    96-well plate pre-coated with anti-Fractalkine/CX3CL1, Human
    Lyophilized recombinant Fractalkine/CX3CL1, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human Fractalkine/CX3CL1 in cell culture supernates, serum and plasma (heparin, EDTA), saliva, urine and human milk.Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice).1, 2 CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. However a soluble (90kD) version of this chemokine has also been observed. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed.2 CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1.3 Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22.2, 4 It can act as a mediator of smooth muscle cell migration in human atherosclerosis, rather than mediate inflammatory cell recruitment.5

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all CX3CL1 ELISA试剂盒

    CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

    别名

    Fractalkine/CX3CL1

    基因ID

    6376

    UniProt

    A0N0N7

    途径

    Synaptic Membrane
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