Cathepsin D ELISA 试剂盒
Quick Overview for Cathepsin D ELISA 试剂盒 (ABIN2042373)
抗原
See all Cathepsin D (CTSD) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 6 pg/mL
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交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 10 pg/mL
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组件
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96-well plate pre-coated with anti-Cathepsin D, Mouse
Lyophilized recombinant Cathepsin D, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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板类型
- Pre-coated
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实验流程
- Sandwich ELISA quantitative detection kit for Mouse Cathepsin D in cell culture supernates, serum and plasma (heparin, EDTA).Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- Cathepsin D (CTSD)
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别名
- Cathepsin D
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基因ID
- 13033
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UniProt
- P18242
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途径
- Peptide Hormone Metabolism
抗原 See all Cathepsin D (CTSD) ELISA试剂盒
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