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APP ELISA 试剂盒

This 人 APP ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 APP.

产品编号 ABIN2042350

发货至: 中国

Quick Overview for APP ELISA 试剂盒 (ABIN2042350)

抗原

See all APP ELISA试剂盒

APP (Amyloid beta (A4) Precursor Protein (APP))

适用

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人

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

2-20000 pg/mL

应用范围

ELISA

Discover our top product APP ELISA Kit

最低检测浓度

2 pg/mL

交叉反应（详细）

There is no detectable cross-reactivity with other relevant proteins.

灵敏度

< 10 pg/mL

组件

96-well plate pre-coated with anti-APP, Human
Lyophilized recombinant APP, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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板类型

Pre-coated

实验流程

Sandwich ELISA quantitative detection kit for Human APP in cell culture supernates, serum and plasma (heparin, EDTA).Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (A ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.

限制

仅限研究用
储存条件

4 °C/-20 °C
抗原 See all APP ELISA试剂盒

APP (Amyloid beta (A4) Precursor Protein (APP))

别名

APP

基因ID

351

UniProt

P05067

途径

Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

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