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ADAM12 ELISA 试剂盒

This 人 ADAM12 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 ADAM12.
产品编号 ABIN2042340
发货至: 中国

Quick Overview for ADAM12 ELISA 试剂盒 (ABIN2042340)

抗原

See all ADAM12 ELISA试剂盒
ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

6-10000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    6 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-ADAM12, Human
    Lyophilized recombinant ADAM12, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human ADAM12 in cell culture supernates, serum, plasma (heparin) and urine.ADAM12 (Disintegrin and metalloproteinase domain-containing protein 12), also known as MLTN, is an enzyme that in humans is encoded by the ADAM12 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. By RT-PCR and immunoblot analyses that expression of mouse Adam12 increases during muscle regeneration, while the levels of other ADAMs remain constant. Immunofluorescence analysis revealed staining of small, newly formed muscle fibers in regenerating but not normal adult muscle cells. By using of fluorescence in situ hybridization, the ADAM12 gene is mapped to human chromosome 10q26.3.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all ADAM12 ELISA试剂盒

    ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

    别名

    ADAM12

    基因ID

    8038

    UniProt

    O43184

    途径

    EGFR Signaling Pathway
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