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SensoLyte® 520 大鼠 Renin Assay Kit

FRET 适用: 大鼠 Fluorometric
产品编号 ABIN1882548
发货至: 中国
  • 抗原 See all Renin (REN) 试剂盒
    Renin (REN)
    适用
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    检测方法
    Fluorometric
    应用范围
    Fluorescence Resonance Energy Transfer Microscopy (FRET)
    品牌
    SensoLyte®
    产品特性
    The SensoLyte® 520 Rat Renin Assay Kit provides a convenient assay for high throughput screening of renin inhibitors and for continuous assay of renin activity using a 5-FAM/QXL™520 fluorescence resonance energy transfer (FRET) peptide. In the FRET peptide the fluorescence of 5-FAM is quenched by QXL™520. Upon cleavage into two separate fragments by renin, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission = 490/520 nm.
    Top Product
    Discover our top product REN ELISA Kit
  • 说明

    FRET-based Assay Kit

    限制
    仅限研究用
  • 注意事项
    Protect Components A and B from light and moisture.
    储存条件
    -80 °C
    储存方法
    Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
  • Matsushima, Furuuchi, Shirai, Nagai, Yokoyama, Nishida, Hirayama: "Effects of acute and chronic boysenberry intake on blood pressure and endothelial function in spontaneous hypertensive rats." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 1, pp. 43-51, (2014) (PubMed).

    Chelko, Schmiedt, Lewis, Lewis, Robertson: "A novel vascular clip design for the reliable induction of 2-kidney, 1-clip hypertension in the rat." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 112, Issue 3, pp. 362-6, (2012) (PubMed).

    Shah, Dhar, El Zahraa Mohammed, Habtesion, Davies, Jover-Cobos, Macnaughtan, Sharma, Olde Damink, Mookerjee, Jalan: "Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression." in: Journal of hepatology, Vol. 56, Issue 5, pp. 1047-53, (2012) (PubMed).

  • 抗原
    Renin (REN)
    别名
    Renin (REN 产品)
    别名
    HNFJ2 Kit, RATRENAA Kit, RENAA Kit, Ren1 Kit, D19352 Kit, Ren Kit, Ren-1 Kit, Ren-A Kit, Ren1c Kit, Ren1d Kit, Rn-1 Kit, Rnr Kit, renin Kit, renin 1 structural Kit, REN Kit, Ren Kit, Ren1 Kit, ren Kit
    背景
    Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels leading to increased blood pressure. Discovery of new renin inhibitors for treatment of hypertension is a promising area of research.
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