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Quick Overview for SensoLyte® 520 Cathepsin S Assay Kit (ABIN1882448)
抗原
See all Cathepsin S (CTSS) 试剂盒检测方法
应用范围
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产品特性
- The SensoLyte® 520 Cathepsin S Activity Assay Kit uses a 5-FAM/QXL™520 labeled FRET peptide substrate for measurement of enzyme activity. In the intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL™ 520. Upon cleavage of the FRET peptide by the active enzyme, the increase of fluorescence can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, the 5-FAM/QXL™ 520 based FRET peptide shows less interference from the autofluorescence of test compounds and cellular components and provides better assay sensitivity.
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Cathepsin S (CTSS) ELISA Kit
CTSS 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Cathepsin S (CTSS) ELISA KitCTSS 适用: 小鼠 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Plasma, Serum, Tissue Homogenate
Cathepsin S (CTSS) ELISA KitCTSS 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
Cathepsin S (CTSS) ELISA KitCTSS 适用: 小鼠 Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Cell Lysate, Plasma, Serum, Tissue Homogenate
Cathepsin S (CTSS) ELISA KitCTSS 适用: 大鼠 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Plasma, Serum, Tissue Homogenate
Cathepsin S (CTSS) ELISA KitCTSS 适用: 人 AA 17-331 Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Cathepsin S (CTSS) ELISA KitCTSS 适用: 猕猴 Colorimetric Sandwich ELISA 28-7.000 pg/mL Cell Culture Supernatant, Plasma, Serum
Cathepsin S (CTSS) ELISA KitCTSS 适用: 人 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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说明
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FRET-based Assay Kit
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限制
- 仅限研究用
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注意事项
- Protect Components A and B from light and moisture.
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储存条件
- -80 °C
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储存方法
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
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: "RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma." in: Cancer research, Vol. 74, Issue 24, pp. 7285-97, (2014) (PubMed).
: "Synthesis of proline analogues as potent and selective cathepsin S inhibitors." in: Bioorganic & medicinal chemistry letters, Vol. 23, Issue 11, pp. 3140-4, (2013) (PubMed).
: "Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II." in: Disease models & mechanisms, Vol. 5, Issue 2, pp. 177-90, (2012) (PubMed).
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: "RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma." in: Cancer research, Vol. 74, Issue 24, pp. 7285-97, (2014) (PubMed).
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- Cathepsin S (CTSS)
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别名
- Cathepsin S
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背景
- Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.
抗原
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