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Rubella Virus Antibody IgG ELISA 试剂盒

The 人 Rubella Virus Antibody IgG ELISA Kit (ABIN1326885) is a Colorimetric ELISA Kit designed to quantify 人 Rubella Virus Antibody IgG.
产品编号 ABIN1326885
发货至: 中国
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Quick Overview for Rubella Virus Antibody IgG ELISA 试剂盒 (ABIN1326885)

抗原

Rubella Virus Antibody IgG

适用

检测方法

Colorimetric

实验类型

Competition ELISA

应用范围

ELISA

样品类型

Serum
  • 原理

    Diluted patient serum is added to wells coated with purified antigen. IgG specific antibody, if present, binds to the antigen. All unbound materials are washed away and the enzyme conjugate is added to bind to the antibody-antigen complex, if present. Excess enzyme conjugate is washed off and substrate is added. The plate is incubated to allow the hydrolysis of the substrate by the enzyme. The intensity of the color generated is proportional to the amount of IgG specific antibody in the sample.

    Analytical Method

    Qualitative
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原

    Rubella Virus Antibody IgG

    别名

    Rubella IgG

    物质类

    Antibody

    背景

    Rubella is usually a mild disease with infrequent complication. In unvaccinated populations, rubella is primarily a childhood disease. Where children are well-immunized, adolescent and adult infections become more evident. Rubella is spread by direct contact with nasal or throat secretions of infected iniduals.Symptoms may include a rash, slight fever, joint aches, headache, discomfort, runny nose and reddened eyes. The incubation period for rubella is 12-23 days in most cases, symptoms appear within 16-18 days. If contracted during the first trimester of pregnancy, Rubella infection can lead to congenital rubella syndrome (CRS). Infection of a pregnant woman may result in a miscarriage, stillbirth or the birth of an infant with abnormalities, which may include deafness, cataracts, heart defects, liver and spleen damage and mental retardation. CRS occurs among at least 25 percent of infants born to women who have had rubella during the first trimester of pregnancy. The presence of IgG antibody to rubella virus is indicative of vaccination or previous exposure. In iniduals with acute rubella infection, four-fold or greater increase in IgG antibody level is indicative of recent infection. Rubella IgM antibodies are detected by ELISA in 100% of patients between days 11-25 after onset of the exanthema, in 60-80% of iniduals at days 15-25 after vaccination and in 90-97% of infants with congenital rubella between 2 weeks and 3 months after birth. Rubella IgM antibody often persists for 20-30 days after acute infection or vaccination.
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