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SNCA ELISA 试剂盒

SNCA 适用: 人 Colorimetric Sandwich ELISA
产品编号 ABIN1059104
发货至: 中国
  • 抗原 See all SNCA ELISA试剂盒
    SNCA (Synuclein, alpha (SNCA))
    适用
    • 8
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    • 6
    • 3
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    Analytical Method
    Quantitative
    产品特性
    This ELISA assay kit provides a standard peptide solution with known concentration to calibrate absorbance readings to concentration.
    组件
    Store all materials at 4 °C:
    • Standard peptide: 0.5 mL
    • Standard diluent: 1.5 mL
    • Microelisa Strip plate: 12 well x 8 strips
    • 6 mL HRP-Conjugate Antibody
    • 30 x wash solution with 25 mL
    • 5 mL Sample diluent
    • 5 mL Chromogen Solution A
    • 5 mL Chromogen Solution B
    • 5 mL Stop Solution
    • Instruction Manual
    • 2 Closure plate membrane
    • Sealed bag
    试剂未包括
    • 37 °C incubator
    • Standard absorbance microplate reader
    • Precision pipettes and disposable pipette tips
    • De-ionized water
    • Disposable tubes for sample dilution
    • Absorbent paper
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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

  • 抗原 See all SNCA ELISA试剂盒
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-Synuclein (SNCA 产品)
    别名
    snca ELISA Kit, MGC64356 ELISA Kit, LOC619283 ELISA Kit, NACP ELISA Kit, alphaSYN ELISA Kit, PARK1 ELISA Kit, PARK4 ELISA Kit, PD1 ELISA Kit, synuclein alpha L homeolog ELISA Kit, alpha-synuclein ELISA Kit, synuclein alpha ELISA Kit, synuclein, alpha ELISA Kit, snca.L ELISA Kit, LOC619283 ELISA Kit, SNCA ELISA Kit, Snca ELISA Kit
    背景
    Alpha-synuclein (SNCA gene) is a 140 amino acid predominantly cytosolic protein expressed in brain associated with fibrillar structures in Lewy Bodies. Although primary located in the cytosol, alpha-synuclein binds to phospholipid and may assemble into pore-like structures in cellular membranes. Generation of aggregates in Lewy Bodies and/or association of alpha-synuclein with membraneous structures have been attributed to the etiology of Parkinson's Disease. Many additional cellular mechanisms associated with abnormal accumulations of alpha-synuclein in brain have also been proposed as underlying etiologies of the disease.
    Parkinson's disease is a complex neurodegenerative disorder characterized by bradykinesia, resting tremor, muscular rigidity and postural instability. Additional features of the disease include the characteristic postural abnormalities, dysautonomia, dystonic cramps, and dementia. The pathology of Parkinson disease involves the loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies in brain and spinal cord.
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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