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KIR2DS4 抗体

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].

54 results

KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7641782
 
KIR2DS4 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C15 unconjugated
产品编号 ABIN7641783
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
产品编号 ABIN7641786
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
产品编号 ABIN7641785
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
产品编号 ABIN7641787
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
产品编号 ABIN7641784
 
KIR2DS4 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7648729
 
KIR2DS4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7570009
 
KIR2DS4 适用: 人 FACS 宿主: 小鼠 Monoclonal APC
产品编号 ABIN339607
 
KIR2DS4 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN327748
 
KIR2DS4 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 5F2 unconjugated
产品编号 ABIN121171
 
KIR2DS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515868
 
KIR2DS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515867
 
KIR2DS4 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C15 unconjugated
产品编号 ABIN1864934
 
KIR2DS4 适用: 人 FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6047160
 
KIR2DS4 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6047102
 
KIR2DS4 适用: 人 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6024692
 
KIR2DS4 适用: 人 WB 宿主: 小鼠 Monoclonal MM0442-2G42 unconjugated
产品编号 ABIN1983329
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7621155
 
KIR2DS4 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C15 unconjugated
产品编号 ABIN7621150
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (IF)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 5F2
    • C15
    • C2
    • C3
    • C4
    • C7
    • MM0442-2G42
  • 抗原表位
    • AA 221-290
    • AA 22-302
    • AA 1-294
    • AA 1-304
    • AA 22-245
    • AA 23-223
    • C-Term
    • Cytoplasmic
    • N-Term
  • 标记
    • 非结合性
    • APC
    • FITC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Biotin
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • HRP
    • PE
  • 抗体亚型
    • IgG
    • IgG2b kappa
    • IgG2a kappa
    • IgG2a
    • IgG2
    • IgG2b
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Abbexa
    • Biomatik
    • Signalway
    • Aviva Systems Biology
    • Cloud-Clone
    • Acris
    • Angio-Proteomie
    • CUSABIO

Latest Publications for our KIR2DS4 抗体

Sim, Rajagopalan, Altmann, Boyton, Sun, Long: "Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 26, pp. 12964-12973, (2019) (PubMed).

Kennedy, Chazara, Gardner, Ivarsson, Farrell, Xiong, Hiby, Colucci, Sharkey, Moffett: "Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 11, pp. 4292-4300, (2017) (PubMed).

Dunphy, Guinan, Chorcora, Jayaraman, Traherne, Trowsdale, Pende, Middleton, Gardiner: "2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells." in: Genes and immunity, Vol. 16, Issue 5, pp. 301-10, (2015) (PubMed).

Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: "Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers." in: Archivum immunologiae et therapiae experimentalis, Vol. 62, Issue 2, pp. 153-60, (2014) (PubMed).

Béziat, Dalgard, Asselah, Halfon, Bedossa, Boudifa, Hervier, Theodorou, Martinot, Debré, Björkström, Malmberg, Marcellin, Vieillard: "CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients." in: European journal of immunology, Vol. 42, Issue 2, pp. 447-57, (2012) (PubMed).

Béziat, Descours, Parizot, Debré, Vieillard: "NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs." in: PLoS ONE, Vol. 5, Issue 8, pp. e11966, (2010) (PubMed).

Aliases for KIR2DS4 抗体

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (KIR2DS4) 抗体
CD158I 抗体
KIR1D 抗体
KIR412 抗体
KKA3 抗体
NKAT8 抗体
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