(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].
DiFranco, Yu, Quiñonez, Vergara: "Inward rectifier potassium currents in mammalian skeletal muscle fibres." in: The Journal of physiology, Vol. 593, Issue 5, pp. 1213-38, (2015) (PubMed).
Cheng, Yung, Covarrubias, Radice: "Cortactin is required for N-cadherin regulation of Kv1.5 channel function." in: The Journal of biological chemistry, Vol. 286, Issue 23, pp. 20478-89, (2011) (PubMed).
Vaidyanathan, Taffet, Vikstrom, Anumonwo: "Regulation of cardiac inward rectifier potassium current (I(K1)) by synapse-associated protein-97." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28000-9, (2010) (PubMed).