The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012].
Bloom: "The UNC-104/KIF1 family of kinesins." in: Current opinion in cell biology, Vol. 13, Issue 1, pp. 36-40, (2001) (PubMed).
Yonekawa, Harada, Okada, Funakoshi, Kanai, Takei, Terada, Noda, Hirokawa: "Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice." in: The Journal of cell biology, Vol. 141, Issue 2, pp. 431-41, (1998) (PubMed).
Okada, Yamazaki, Sekine-Aizawa, Hirokawa: "The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors." in: Cell, Vol. 81, Issue 5, pp. 769-80, (1995) (PubMed).
Aliases for KIF1A 抗体
kinesin family member 1A (KIF1A) 抗体 kinesin family member 1A (kif1a) 抗体 kinesin family member 1A (Kif1a) 抗体 kinesin family member 1Aa (kif1aa) 抗体 ATSV 抗体 C2orf20 抗体 C630002N23Rik 抗体 Gm1626 抗体 HSN2C 抗体 Kns1 抗体 MRD9 抗体 SPG30 抗体 UNC104 抗体