(Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
Wang, Zankov, Jiang, Zhang, Henderson, Tseng: "[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes." in: The Journal of biological chemistry, Vol. 288, Issue 49, pp. 35358-71, (2013) (PubMed).
Aliases for KCNE1 抗体
potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog (kcne1.L) 抗体 potassium voltage-gated channel, Isk-related family, member 1 (KCNE1) 抗体 potassium voltage-gated channel subfamily E member 1 (LOC474097) 抗体 potassium voltage-gated channel subfamily E regulatory subunit 1 (KCNE1) 抗体 potassium voltage-gated channel subfamily E regulatory subunit 1 (Kcne1) 抗体 potassium voltage-gated channel, Isk-related subfamily, member 1 (Kcne1) 抗体 isk 抗体 ISK 抗体 Isk 抗体 IsK 抗体 jlns 抗体 JLNS 抗体 jlns2 抗体 JLNS2 抗体 KCNE1 抗体 LQT2/5 抗体 LQT5 抗体 m 抗体 mink 抗体 MinK 抗体 minK 抗体 nmf190 抗体 xkcne1 抗体