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KCND2 产品

(Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008].

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KCND2 抗体

High quality antibodies with extensive validation data.

KCND2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our KCND2 Products

Mulholland, Spencer, Hu, Kroener, Chandler: "Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus." in: Psychopharmacology, Vol. 232, Issue 11, pp. 1995-2006, (2015) (PubMed).

Jensen, Misonou: "Live-cell imaging of post-golgi transport vesicles in cultured hippocampal neurons." in: Cellular and molecular neurobiology, Vol. 35, Issue 1, pp. 123-35, (2015) (PubMed).

Lopez-Izquierdo, Pereira, Wende, Punske, Abel, Tristani-Firouzi: "The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization." in: American journal of physiology. Heart and circulatory physiology, Vol. 306, Issue 5, pp. H747-54, (2014) (PubMed).

Jensen, Watanabe, Rasmussen, Schmitt, Olesen, Frost, Blanpied, Misonou: "Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons." in: The Journal of biological chemistry, Vol. 289, Issue 15, pp. 10566-81, (2014) (PubMed).

Dufour, Woodhouse, Goaillard: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).

Lugo, Smith, Arbuckle, White, Holley, Floruta, Ahmed, Gomez, Okonkwo: "Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins." in: Frontiers in molecular neuroscience, Vol. 7, pp. 27, (2014) (PubMed).

Lin, Long, Hatch, Hoffman: "DPP6 domains responsible for its localization and function." in: The Journal of biological chemistry, Vol. 289, Issue 46, pp. 32153-65, (2014) (PubMed).

Chang, Atzmon, Bergman, Brugmann, Atwood, Chang, Barzilai: "Identification of genes promoting skin youthfulness by genome-wide association study." in: The Journal of investigative dermatology, Vol. 134, Issue 3, pp. 651-7, (2014) (PubMed).

Xu, Wu, Grabauskas, Owyang: "Butyrate-induced colonic hypersensitivity is mediated by mitogen-activated protein kinase activation in rat dorsal root ganglia." in: Gut, Vol. 62, Issue 10, pp. 1466-74, (2013) (PubMed).

Kaufmann, Matsui, Jeromin, Nerbonne, Ferraguti: "Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression." in: Brain structure & function, Vol. 218, Issue 5, pp. 1115-32, (2013) (PubMed).

Synonyms and alternative names related to KCND2

potassium voltage-gated channel subfamily D member 2 (KCND2), potassium voltage-gated channel, Shal-related subfamily, member 2 (KCND2), potassium voltage-gated channel subfamily D member 2 (kcnd2), potassium voltage-gated channel, Shal-related subfamily, member 2 (kcnd2), potassium voltage-gated channel, Shal-related family, member 2 (Kcnd2), potassium voltage-gated channel subfamily D member 2 (LOC101669961), potassium voltage-gated channel subfamily D member 2 (Kcnd2), AI839615, AW555701, DKFZp459P1550, KCND2, Kv4.2, KV4.2, mKIAA1044, R75121, RK5, Shal1, si:dkey-24j9.3, si:dkeyp-97c5.3

Protein level used designations for KCND2

  • potassium voltage-gated channel, Shal-related subfamily, member 2
  • potassium voltage-gated channel Sha1-related subfamily member 2
  • potassium voltage-gated channel subfamily D member 2
  • zShal2
  • potassium channel Kv4.2
  • voltage-gated potassium channel subunit Kv4.2
  • voltage-gated potassium channel Kv4.2
  • voltage-sensitive potassium channel
  • Potassium voltage-gated channel subfamily D member 2
  • Voltage-gated potassium channel subunit Kv4.2
  • potassium channel alpha subunit Kv4.2
  • potassium voltage gated channel, Shal-related family, member 2
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