KCNA3 抗体
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].
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Latest Publications for our KCNA3 抗体
: "K+ channels expression in hypertension after arterial injury, and effect of selective Kv1.3 blockade with PAP-1 on intimal hyperplasia formation." in: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, Vol. 28, Issue 6, pp. 501-11, (2014) (PubMed).: "Blockade of Kv1.3 channels ameliorates radiation-induced brain injury." in: Neuro-oncology, Vol. 16, Issue 4, pp. 528-39, (2014) (PubMed).
: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).
: "Kv1.3 in psoriatic disease: PAP-1, a small molecule inhibitor of Kv1.3 is effective in the SCID mouse psoriasis--xenograft model." in: Journal of autoimmunity, Vol. 55, pp. 63-72, (2014) (PubMed).
: "Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis." in: The Journal of comparative neurology, Vol. 521, Issue 5, pp. 1184-201, (2013) (PubMed).
: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." in: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).
: "Expression of Kv1.3 potassium channels regulates density of cortical interneurons." in: Developmental neurobiology, Vol. 73, Issue 11, pp. 841-55, (2013) (PubMed).
: "Kv1.3 inhibitors have differential effects on glucose uptake and AMPK activity in skeletal muscle cell lines and mouse ex vivo skeletal muscle." in: The journal of physiological sciences : JPS, Vol. 64, Issue 1, pp. 13-20, (2013) (PubMed).
: "Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1338-56, (2012) (PubMed).
: "N-glycosylation promotes the cell surface expression of Kv1.3 potassium channels." in: The FEBS journal, Vol. 279, Issue 15, pp. 2632-44, (2012) (PubMed).
Aliases for KCNA3 抗体
potassium voltage-gated channel subfamily A member 3 (KCNA3) 抗体potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog (kcna3.S) 抗体
potassium voltage-gated channel, shaker-related subfamily, member 3 (Kcna3) 抗体
potassium voltage-gated channel subfamily A member 3 (Kcna3) 抗体
cKv1.1 抗体
HGK5 抗体
HLK3 抗体
HPCN3 抗体
HUKIII 抗体
Kca1-3 抗体
kcna3b-a 抗体
kv1.3 抗体
KV1.3 抗体
Kv1.3 抗体
Kv1.3-glyb 抗体
Kv1.3B 抗体
Mk-3 抗体
MK3 抗体
PCN3 抗体
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