Recombinant 人 IgG4 同型对照
In vivo Grade
IsoC, in vivo
IgG4
Recombinant Antibody
unconjugated
产品编号 ABIN7211744
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant 人 IgG4 同型对照 (ABIN7211744)
抗原
IgG4
抗体类型
Recombinant Antibody
应用范围
Isotype Control (IsoC), In vivo Studies (in vivo)
质量等级
In vivo Grade
亚型
IgG4
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适用
- 人
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宿主
- Human
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Expression System
- Mammalian cells
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原理
- In Vivo Grade Recombinant Human IgG4 Fc Protein
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产品特性
- Human IgG4 Fc is the tail region of the immunoglobulin G4 (IgG4) that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. The ~230 amino acid fragment generally exists as a dimer, although under reducing conditions, it exists as a monomer. It is the basis of prolonged pharmacokinetics of antibodies and is commonly used as a fusion to extend half-life of fusion proteins. IgG4's hinge is shorter than that of IgG1, its flexibility is intermediate between IgG1 and IgG2 and some rotation may occur around the glycine residue in its hinge region.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by SDS-PAGE under reducing conditions
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过滤
- Sterile filtered
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存条件
- 4°C,-20 °C
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储存方法
- 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
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有效期
- 3 months
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- IgG4
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物质类
- Antibody
抗原
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