Recombinant 人 IgG2 同型对照
In vivo Grade
IsoC, in vivo
IgG2
Recombinant Antibody
unconjugated
产品编号 ABIN7211742
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant 人 IgG2 同型对照 (ABIN7211742)
抗原
IgG2
抗体类型
Recombinant Antibody
应用范围
Isotype Control (IsoC), In vivo Studies (in vivo)
质量等级
In vivo Grade
亚型
IgG2
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适用
- 人
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宿主
- Human
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Expression System
- Mammalian cells
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原理
- In Vivo Grade Recombinant Human IgG2 Fc Protein
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产品特性
- Human Fc (IgG2) is the tail region of an immunoglobulin G2 (IgG2) that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. The ~230 amino acid fragment generally exists as a dimer, although under reducing conditions, it exists as a monomer. It is the basis of prolonged pharmacokinetics of antibodies and is commonly used as a fusion to extend half-life of fusion proteins. IgG2 has a shorter hinge than IgG1, with 12 amino acid residues and four disulfide bridges at the Fab base. The hinge region of IgG2 also lacks a glycine residue, which along with its shortness almost completely prevents rotation and restricts lateral movement of the Fabs.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by SDS-PAGE under reducing conditions
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过滤
- Sterile filtered
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存条件
- 4°C,-20 °C
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储存方法
- 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
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有效期
- 3 months
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- IgG2
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物质类
- Antibody
抗原
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