蛋白简介

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Alternative names and synonyms associated with MED17

• mediator of RNA polymerase II transcription subunit 17 (AOR_1_2446154) 抗体
• mediator of RNA polymerase II transcription subunit 17 (VDBG_01663) 抗体
• mediator complex subunit 17 (med17) 抗体
• mediator complex subunit 17 L homeolog (med17.L) 抗体
• mediator complex subunit 17 (MED17) 抗体
• 显示所有的基因名称
• mediator complex subunit 17 (Med17) 抗体

• 77kDa 抗体
• C330002H14Rik 抗体
• Crsp6 抗体
• CRSP77 抗体
• DRIP80 抗体
• 显示所有的同义词和别名
• Trap80 抗体

Protein level used designations for MED17

mediator of RNA polymerase II transcription subunit 17 , Mediator of RNA polymerase II transcription subunit 17 , CRSP complex subunit 6 , cofactor required for Sp1 transcriptional activation subunit 6 , cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa , ARC77 , activator-recruited cofactor 77 kDa component , thyroid hormone receptor-associated protein complex 80 kDa component , transcriptional coactivator CRSP77 , vitamin D3 receptor-interacting protein complex 80 kDa component , cofactor required for Sp1 transcriptional activation, subunit 6 (77kD) , cofactor required for Sp1 transcriptional activation, subunit 6