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Trichostatin A

Inh Cell-permeable 58880-19-6 (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
产品编号 ABIN7233302
发货至: 中国

Quick Overview for Trichostatin A (ABIN7233302)

应用范围

Inhibition (Inh)

Chemical Name

(2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide

Permeability

Cell-permeable
  • 原理

    HDAC inhibitor

    产品特性

    Potent and selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces reversion of ras transformed cells to normal morphology. Induces dedifferentiation of primordial germ cells into embryonic germ cells. Cell permeable and active in vivo.

    纯度

    >98 %

    Formula

    C17H22N2O3

    Solubility

    Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
  • 限制

    仅限研究用
  • 状态

    Powder

    储存条件

    -20 °C
  • 背景

    TSA,Apoptosis inducer,Epigenetics,Cell cycle,Protein deacetylase,Stem cells,Cell death,Cancer,Infectious disease,Posttranslational modification,Chromatin

    分子量

    302.38

    CAS-编号

    58880-19-6
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