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Triacetylresveratrol

Act 42206-94-0 5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate

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产品编号 ABIN7233301

发货至: 中国

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Quick Overview for Triacetylresveratrol (ABIN7233301)

应用范围

Activation (Act)

Chemical Name

5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate

原理

SIRT activator, prodrug

产品特性

A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. CWR22Rv1 cells when exposed to triacetyl resveratrol showed a G1S block concomitant with increased p53 and p21 expression. In MCF-7 cells it induced both ERK and p38 phosphorylation.

纯度

>98 %

Formula

C20H28O6

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
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限制

仅限研究用
状态

Powder

储存条件

-20 °C
背景

3,5,4'-Tri-O-acetylresveratrol,NFkappaB,Epigenetics,Apoptosis inducer,Hedgehog,PI3K,Protein deacetylase,Antioxidant,Cell death,Immunology,Cancer,Diabetes,Ageing,Posttranslational modification,Inflammation,Chromatin

分子量

364.4

CAS-编号

42206-94-0