Quick Overview for TC-E 5003 (ABIN7233297)
应用范围
Chemical Name
-
-
原理
- Arginine methyl transferase 1 (PRMT1) inhibitor
-
产品特性
- Selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 μM. Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells.
-
纯度
- >98 %
-
Formula
- C16H14Cl2N2O4S
-
Solubility
- Soluble in DMSO (up to 50 mg/ml).
-
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
AS-8351Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
UNC-0379Inh 1620401-82-2 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)-pentyl)quinazolin-4-amine
-
-
限制
- 仅限研究用
-
-
-
状态
- Powder
-
储存条件
- -20 °C
-
-
-
背景
- Epigenetics,Transcription,Protein methyltransferase,Posttranslational modification,Chromatin
-
分子量
- 401.26
-
CAS-编号
- 17328-16-4
-
-
