Panobinostat
-
- 应用范围
- Inhibition (Inh)
- 原理
- HDAC inhibitor
- 产品特性
- A potent inhibitor of class I and II HDACs. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells. A potent antimyeloma agent that overcomes drug resistance.
- 纯度
- >98 %
- Chemical Name
- (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
- Formula
- C21H23N3O2
- Solubility
- Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
Santacruzamate AInh 1477949-42-0 N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester
-
- 限制
- 仅限研究用
-
- 状态
- Powder
- 储存条件
- -20 °C
-
- 背景
- LBH-589,Epigenetics,Apoptosis inducer,Protein deacetylase,Cell death,Cancer,Posttranslational modification,Chromatin
- 分子量
- 349.44
- CAS-编号
- 404950-80-7
-
