HPA (Hexyl-4-pentynoic acid)
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北京 101111
Quick Overview for HPA (Hexyl-4-pentynoic acid) (ABIN7233260)
应用范围
Chemical Name
Permeability
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原理
- HDAC inhibitor
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产品特性
- Histone deacetylase (HDAC) inhibitor, IC50=13 μM. More potent and robust than valproic acid at inducing histone hyperacetylation (600 % at 50 μM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons. Cell permeable.
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纯度
- >98 %
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Formula
- C11H18O2
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Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
AS-8351Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
UNC-0379Inh 1620401-82-2 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)-pentyl)quinazolin-4-amine
GSK3326595Inh 1616392-22-3 6-[(1-Acetylpiperidine-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide
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限制
- 仅限研究用
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状态
- Oil
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储存条件
- RT
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背景
- HPA,Epigenetics,Protein deacetylase,Posttranslational modification,Chromatin
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分子量
- 182.27
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CAS-编号
- 96017-59-3
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