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EX-527

Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
产品编号 ABIN7233252
发货至: 中国

Quick Overview for EX-527 (ABIN7233252)

应用范围

Inhibition (Inh)

Chemical Name

6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)

Permeability

Cell-permeable
  • 原理

    SIRT1 inhibitor

    产品特性

    Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.

    纯度

    >98 %

    Formula

    C13H13ClN2O

    Solubility

    Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).
  • 限制

    仅限研究用
  • 状态

    Powder

    储存条件

    -20 °C
  • 背景

    Epigenetics,p53,Protein deacetylase,Stem cells,Neuroscience,Ageing,Neurodegeneration,Posttranslational modification,Chromatin

    分子量

    248.7

    CAS-编号

    49843-98-3
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