EX-527
Quick Overview for EX-527 (ABIN7233252)
应用范围
Chemical Name
Permeability
-
-
原理
- SIRT1 inhibitor
-
产品特性
- Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.
-
纯度
- >98 %
-
Formula
- C13H13ClN2O
-
Solubility
- Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Powder
-
储存条件
- -20 °C
-
-
-
背景
- Epigenetics,p53,Protein deacetylase,Stem cells,Neuroscience,Ageing,Neurodegeneration,Posttranslational modification,Chromatin
-
分子量
- 248.7
-
CAS-编号
- 49843-98-3
-
-