EX-527
Quick Overview for EX-527 (ABIN7233252)
应用范围
Chemical Name
Permeability
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    - 
                                            原理
- SIRT1 inhibitor
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                                            产品特性
- Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.
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                                            纯度
- >98 %
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                                            Formula
- C13H13ClN2O
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                                            Solubility
- Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).
 
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    - 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Powder
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                                            储存条件
- -20 °C
 
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    - 
                                            背景
- Epigenetics,p53,Protein deacetylase,Stem cells,Neuroscience,Ageing,Neurodegeneration,Posttranslational modification,Chromatin
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                                            分子量
- 248.7
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                                            CAS-编号
- 49843-98-3
 
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