Ruxolitinib
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- 应用范围
- Inhibition (Inh)
- 原理
- JAK kinase inhibitor
- 纯度
- >98 %
- Chemical Name
- (3R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
- Formula
- C17H18N6
- Solubility
- Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml)
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- 说明
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Source: Synthetic.
Appearance: Off-white solid - 限制
- 仅限研究用
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- 状态
- Solid
- 注意事项
- Classification: Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Danger Target Organ Systemic Toxicity (repeated exposure), Category 2 Toxic To Reproduction, Category 2 Warning Acute Toxicity: Oral, Category 4 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315: Causes skin irritation. H318: Causes serious eye damage H373: May cause damage to organs through prolonged or repeated exposure. H361: Suspected of damaging fertility or the unborn child. H302: Harmful if swallowed. Precautionary statements: P264: Wash hands thoroughly after handling. P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent authority. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P302+352: IF ON SKIN: Wash with plenty of soap and water. P332+313: If skin irritation occurs, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attentiodvice if you feel unwell. P308+313: IF exposed or concerned: Get medical attentiodvice. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth.
- 注意事项
- Classification: Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Danger Target Organ Systemic Toxicity (repeated exposure), Category 2 Toxic To Reproduction, Category 2 Warning Acute Toxicity: Oral, Category 4 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315: Causes skin irritation. H318: Causes serious eye damage H373: May cause damage to organs through prolonged or repeated exposure. H361: Suspected of damaging fertility or the unborn child. H302: Harmful if swallowed. Precautionary statements: P264: Wash hands thoroughly after handling. P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent authority. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P302+352: IF ON SKIN: Wash with plenty of soap and water. P332+313: If skin irritation occurs, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attentiodvice if you feel unwell. P308+313: IF exposed or concerned: Get medical attentiodvice. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth.
- 储存条件
- -20 °C
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- 分子量
- 306.4
- CAS-编号
- 941678-49-5
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