Indometacin
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- 应用范围
- Inhibition Assay (InhA), Functional Studies (Func)
- 原理
- Indomethacin is a non-steroidal antiinflammatory agent (NSAIA) with antiinflammatory, analgesic and antipyretic activity. Its pharmacological effect is thought to be mediated through inhibition of the enzyme cyclooxygenase (COX), the enzyme responsible for catalyzes the rate-limiting step in prostaglandin synthesis via the arachidonic acid pathway.
- 产品特性
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Tradename: INDOCIN
Source of Compound: synthetic
Target: COX inhibitor,PPAR agonist
Receptor: Prostaglandin G/H synthase 1,2,PTGR1,PPARα,PPARγ
- 纯化方法
- All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
- 纯度
- 98 %
- Formula
- C19H16ClNO4
- Solubility
- DMSO 72 mg/mL, Water <1 mg/mL
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Solid
- 储存条件
- -20 °C
- 储存方法
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For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. - 有效期
- 24 months
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- 背景
- Neuroscience
- 分子量
- 357.79 g/mol
- CAS-编号
- 53-86-1
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