Conantokin G
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北京 101111
Quick Overview for Conantokin G (ABIN1540037)
应用范围
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原理
- Conantokin G inhibits NMDA receptors
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序列
- Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
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特异性
- Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT).
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限制
- 仅限研究用
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分子量
- 2264.23 Da
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CAS-编号
- 93438-65-4
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