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Felodipine

BR, Inh 72509-76-3 Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Plendil
产品编号 ABIN1027921
发货至: 中国
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Quick Overview for Felodipine (ABIN1027921)

应用范围

Blocking Reagent (BR), Inhibition (Inh)

Chemical Name

Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Plendil
  • 原理

    L-type Ca channel blocker

    产品特性

    L-type Ca channel blocker.

    纯度

    >98 % (TLC), NMR (Conforms)

    Formula

    C18H19Cl2NO4

    Solubility

    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • 说明

    Source: Synthetic.
    Appearance: Light Yellow Solid

    限制

    仅限研究用
  • 状态

    Solid

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302

    储存条件

    -20 °C
  • 背景

    Felodipine is an L-type Ca2+ channel blocker. In isolated rat ventricular myocytes, using a whole-cell patch-clamp technique, it displays a Ki of 11 nM. It is a clinically useful antihypertensive agent which attenuates the hypertrophic effect of cyclosporine on transplanted hearts.

    分子量

    384.25

    CAS-编号

    72509-76-3
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