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Mifepristone (RU486)

Inh 84371-65-3 (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one, RU486, RU 38486
产品编号 ABIN1027778
发货至: 中国
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Quick Overview for Mifepristone (RU486) (ABIN1027778)

应用范围

Inhibition (Inh)

Chemical Name

(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one, RU486, RU 38486
  • 原理

    Glucocorticoid antagonist

    产品特性

    Glucocorticoid antagonist.

    纯度

    >98 %

    Formula

    C29H35NO2

    Solubility

    Soluble to 100 mM in DMSO, and to 50 mM in ethanol
  • 说明

    Source: Synthetic.
    Appearance: Yellow solid

    限制

    仅限研究用
  • 状态

    Solid

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H360 Precautionary Phrases: P201-P308 + P313

    注意事项

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H360 Precautionary Phrases: P201-P308 + P313

    储存条件

    -20 °C
  • 背景

    Mifepristone is a progesterone receptor antagonist used as an abortifacient. It is also an antiglucocorticoid and an antiandrogen. Its relative binding affinity at the progesterone receptor is twice that of progesterone, its affinity at the glucocorticoid receptor is 3x that of dexamethasone, and more than 10 times that of cortisol.

    分子量

    429.6

    CAS-编号

    84371-65-3
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